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Vesicoureteral Reflux


Overview :

The normal flow of urine begins in the collecting system of each kidney. Urine then flows out of each kidney and into a tube called the ureter. Each ureter leads into the bladder, where the urine collects until it is passed out of the body. Normally, urine should flow only in this direction. In vesicoureteral reflux, however, urine that has already collected in the bladder is able to flow backwards from the bladder, up the ureter, and back into the collecting system of the kidney. VUR may be present in either one or both ureters.

Vesicoureteral reflux causes damage to the kidneys in two ways:

  • The kidney is not designed to withstand very much pressure. When VUR is present, back pressure of the urine on the kidney is significant. This can damage the kidney.
  • The kidney is usually sterile, meaning that no bacteria are normally present within it. In VUR, bacteria that enter through the urinary tract may be carried back up the ureter with the urine. These bacteria can enter the kidney, causing severe infection.




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