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EDITOR'S PICK

Rheumatoid arthritis (RA) is a chronic, systemic inflammatory disorder that may affect many tissues and organs, but principally attacks synovial joints. The process produces an inflammatory response of the synovium (synovitis) secondary to hyperplasia of synovial cells, excess synovial fluid, and the development of pannus in the synovium.

Various treatments are available. Non-pharmacological treatment includes physical therapy, orthoses, occupational therapy and nutritional therapy. Analgesia (painkillers) and anti-inflammatory drugs, including steroids, are used to suppress the symptoms, while disease-modifying antirheumatic drugs (DMARDs) are often required to inhibit or halt the underlying immune process and prevent long-term damage.

http://en.wikipedia.org/wiki/Rheumatoid_Arthritis

Dr. Allan Gibofsky, MD, JD

The clinical picture of rheumatoid arthritis (RA) is the result of a complex cascade involving T cells, B cells, antigen-presenting cells, and a complex set of costimulatory signals that lead to the production of proinflammatory cytokines, including tumor necrosis factor (TNF)-alpha, interleukins, and other mediators. Recent treatment options have targeted different components of the intracellular cascade, proinflammatory cytokines, some patients continue to show disease progression.

http://cme.medscape.com/viewarticle/584156

Wikipedia

Expert's Comment

Latest Medical Breakthroughs

Rheumatoid arthritis (RA) is an autoimmune disease that causes chronic inflammation of the joints. Rheumatoid arthritis can also cause inflammation of the tissue around the joints, as well as in other organs in the body. Autoimmune diseases are illnesses that occur when the body's tissues are mistakenly attacked by their own immune system.

Latest Headlines

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The American College of Rheumatology today announced the release of revised classification criteria (created in collaboration with the European League Against Rheumatism ) for rheumatoid arthritis , which will ...
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Top Stories

Rheumatoid Arthritis Overview - WebMD Average Rating 0%

WebMD give you basic information about the causes, symptoms, diagnosis, and treatments for rheumatoid arthritis.
http://www.webmd.com

CDC - Arthritis - Basics - Definition - Rheumatoid Arthritis Average Rating 0%

Centers for Disease Control and Prevention - Your Online Source for Credible Health Information
http://www.cdc.gov

Rheumatoid Arthritis: MedlinePlus Average Rating 0%

Rheumatoid arthritis (RA) is a form of arthritis that causes pain, swelling, stiffness and loss of function in your joints. It can affect any joint but is common in the wrist and ...
http://www.nlm.nih.gov

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Community & Support

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I have been recently diagnosed with RA, kind of. The symptoms are all there but the blood work doesnt show it. I literally woke up one morn...
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I have been diagnosed with Rheumatoid arthritis. Does rheumatoid arthritis affect your teeth and gums? I have been having alot of trouble with my teeth.
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Rheumatoid Arthritis | A chronic systemic disease characterised by inflammatory changes in joints & related structures that results in crippling
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