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Hepatitis, Drug-Induced


Overview :

The liver is a very important organ to the body. It is a large internal organ weighing more than three pounds in the average adult. It performs over 100 functions including formation of bile, detoxification of harmful substances, vitamin storage and metabolism of carbohydrates, fats and proteins. Serious complications could arise when the liver becomes inflamed due to hepatitis when it is not able to perform these tasks. A virus most often causes hepatitis but certain drugs can also induce it.

Drug-induced hepatitis (also called toxic hepatitis) occurs in eight in every 10,000 people because the liver reacts abnormally during drug exposure, leading to liver damage. This pathology causes the liver not to function properly and the symptoms can begin to be seen. Women tend to be affected almost twice as often as men. Older people are more prone to this type of hepatitis because their bodies aren't able to repair themselves as fast as younger people. Drugs that can be associated with drug-induced hepatitis include acetaminophen, vitamin A, and PTU (a drug treatment for tuberculosis).




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